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Time of onset and duration of action of cannabinoids

by - Posted 7 years ago

We often are asked about how long it takes to feel the effects of cannabis products given the different routes of administration.

Here is a primary source answering these questions:

been used in a few studies and are of little relevance in practice today. The pharmacoldnetics of THC vary as a function of its route of administration. Pulmonary assimilation of inhaled THC causes a maximum plasma concentration within minutes, psychotropic effects start within seconds to a few Min.., reach a maximum after 1.5-3o minutes, and taper off within 2-3 hours. Following oral ingestion, psychotropic effects set in with a delay of 30-90 minutes, reach their maximum after a-3 hours and last for about 4,2 hours, depending on dose and specific effect

The paper here is one of the peer reviewed papers we base our comments on:

https://link.springer.com/article/10.2165%2F00003088-200342040-00003